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CDSCO

CDSCO Issues Circular on Indiscriminate Use of NSAIDs and Antibiotics


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Importer & Manufacturer   |   Source: CDSCO
Published On: 22-09-2026

Enforcement Date: 21 September, 2026
CDSCO Issues Circular on Indiscriminate Use of NSAIDs and Antibiotics

The Central Drugs Standard Control Organisation (CDSCO) has issued a circular highlighting the risks associated with indiscriminate use of non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics, including chronic kidney disease and antimicrobial resistance. The circular advises healthcare professionals, pharmacists, retailers, hospitals and the public on responsible medicine use and reiterates compliance with prescription requirements under the Drugs Rules, 1945.


The Central Drugs Standard Control Organisation (CDSCO) has issued a circular dated 21 September 2026 concerning the indiscriminate use of NSAIDs and antibiotics and their associated health risks.


Key points include:

  1. NSAIDs and antibiotics should be used only when clinically indicated, at appropriate doses and for the prescribed duration under medical supervision.
  2. Prolonged or repeated NSAID use may increase the risk of kidney impairment, particularly in vulnerable patients.
  3. Healthcare professionals should prescribe the lowest effective NSAID dose for the shortest appropriate duration and use antibiotics judiciously.
  4. Antibiotics should not be used for self-medication or shared with others.
  5. Schedule H and H1 medicines must be sold in compliance with prescription requirements under the Drugs Rules, 1945.
  6. Pharmacists and retailers must comply with applicable sale conditions and prescribed warnings.
  7. State and Union Territory Drugs Control Authorities are requested to promote awareness and ensure regulatory compliance.

Applicable For: Importer & Manufacturer
Reference Number: F. No. Legal-11018(11)/177/2026-eoffice Notification Link

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